周树堂优配都季困杨聚,男,博士,研究员候带笔改,博士生导师;中国科学院动物研究所昆虫发育与生殖基因调控研究组组长。
1981-09-01-1985-06-30 河南农业大学 本科
1998-06-15-2002-12-措培以乎适有做30 加拿大Queen's University 博士
2002年毕业于加拿大Q来自ueen's University,获生物化学和分子生物学博士学位。2003-2360百科004年在Queen's University蛋白质功能中心和生物化学系从事博士后研究,2005年后在美国Duke University Medical Center任助理研究员、助理教授。2009年入选中国科学院"百人计划",2010年起担任中国科学院动物研究所研究员、博士生导师、昆虫发育与生殖基因调控研究组组长,2011年获"百人计划"择优支持。
长期从事发育生物刑的异夜房长学,转录调控机制,细胞因子与信号通路,功能基因进化及环境胁迫适应等方面的研究。曾获美国PRS NIH/NICHD Young Investigator Award,担任Journal of Allergy and Therapy编委。近年的研究成果发表于PNAS, Insect Bio看输预孔术造规西chemistry and Molecular Biology, Journal of Cell Science, American Journal of Physiology等SCI期刊上。授权国际专利1项。
综合运用分子生物学扬输变室、生物化学、细胞生物学等手段,研究昆虫生殖发育与变态的基因调控机制,昆虫与寄主植物的相互作用和昆虫适应环境胁迫的分子机理。包括昆虫激素(保幼因激素、蜕皮激素、肽激素等)或环境与寄主因子诱导下的基因转录与调控、蛋白表达与修饰、信号传导等。
1、S. Zhou*, E.Potts, F. Cuttitta, W来自.M. Foster, and M.E. Sunday*. Gastrin-releasing peptide blockade: b球厂road-spectrum anti-inflamm方做史宽必atory therapy for asthma.* Co-corresponding authors. Submitted.
2360百科、S. Zhou, S. Degan, E.N. Potts, W.M. Foster and M.E. Sunday. 2009. NPAS3 is a trachealess homol生医养具测关晚士缺集雨og critical for lung development and homeostasis. Proceeding of the National Academy of Science. 106, 11699–11704.
3、B.M. Levesque*, S. Zhou*, L. Shan, Y. Kong and M.E. Sunday. 2007. NPAS1 regulates branching morphogenesis in embryonic lung. American Journa厚台开米范林买讨渐表l of Respiratory Cell and Molecular Biology. 36, 427-434. * contributed equally as co-first aut即关宁氧若入地弱培hors
4、S. Zhou, M. Tejada, G.R. Wyatt, V.K. Walker. 2006. A DNA-binding protein, tfp1, involved in juvenile hormone-regulat客导宁值煤班草ed gene expression in 亚七家田而乎工问Locusta migratoria. Insect Biochemistry and Mo或源lecular Biology. 目甲白响绝富田争法36: 724-73展4.
5、S. Zhou, B.A. Webb, R. Eves, and A.S. Mak. 2006. Effects of Tyr-phosphorylation o代守困矛座孔花丰f cortactin on podosome-formation in A7r5 vas点意谈销神探cular smoo何审差控th muscle cells妈爱之滑检语服大热. AJP-Cel载绝我额反西化课养否认l Physiology.290, C463-4沉光己积严物呢71.
6、B.A. Webb, S. Zhou, R. Eves, and A.S. Mak. 2006. Phosphorylation of cortactin by p21-activated kinase. Archives of Biochemistry Biophysics. 456, 183-193.
7、R. Eves, B.A. Webb, S. Zhou, and A.S. Mak. 2006. Caldesmon is an integral component of podosomes in smooth muscle cells. Journal of Cell Science. 119, 1691-1702.
8、B.A. Webb, R. Eves, S. Crawley, S. Zhou, G.P., Côté and A.S. Mak. 2005. p21-activated kinase induces podosome formation in A7r5 vascular smooth muscle cells in a PIX-dependent manner. AJP-Cell Physiology. 289: C898-907.
9、D.C. Hayward, T.S. Dhadialla, S. Zhou, M.J. Kuiper, E.E. Ball, G.R. Wyatt, V.K. Walker. 2003. Ligand specificity and developmental expression of RXR and ecdysone receptor in the migratory locust. Journal of Insect Physiology. 49, 1135-1144.
10、S. Zhou, J. Zhang, M. Hirai, Y. Chinzei, H. Kayser, G.R. Wyatt, V.K. Walker. 2002. A DNA-binding protein involved in gene regulation by juvenile hormone. Molecular and Cellular Endocrinology. 190, 177-185.
11、S. Zhou, J. Zhang, M.D. Fam, G.R. Wyatt, V.K. Walker. 2002. Sequences of elongation factors-1a and -1g and stimulation by juvenile hormone in Locusta migratoria. Insect Biochemistry and Molecular Biology. 32, 1567-1576.
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